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Oral supplementation with yeast β-glucans improves the resolution of Escherichia coli-associated inflammatory responses independently of monocyte/macrophage immune training

Sarah Walachowski , Koen Breyne , Thomas Secher , Céline Cougoule , Laurence Guzylack-Piriou et al.
Frontiers in Immunology, 2022, 13, pp.1086413. ⟨10.3389/fimmu.2022.1086413⟩
Journal articles hal-03957147v1

CD1 and MR1: An update after a long-awaited reunion

Nicholas A Gherardin , Francois Legoux , Michela Consonni , Christophe Paget
Immunity, 2022, 55 (12), pp.2211-2216. ⟨10.1016/j.immuni.2022.11.008⟩
Journal articles hal-03930413v1

Neutrophils play a major role in the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters

Clara Bourgon , Audrey St Albin , Ophélie Ando-Grard , Bruno da Costa , Roxane Domain et al.
Cellular and Molecular Life Sciences, 2022, 79 (12), pp.616. ⟨10.1007/s00018-022-04643-1⟩
Journal articles hal-03918364v1
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Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection

Olivier Reynard , Claudia Gonzalez , Claire Dumont , Mathieu Iampietro , Marion Ferren et al.
Preprints, Working Papers, ... hal-03777084v1
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Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial

Nicolas Fage , Julien Demiselle , Valérie Seegers , Hamid Merdji , Fabien Grelon et al.
Annals of Intensive Care, 2022, 12, ⟨10.1186/s13613-022-01053-1⟩
Journal articles hal-03980601v1
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Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa

Karin Santoni , David Pericat , Leana Gorse , Julien Buyck , Miriam Pinilla et al.
PLoS Pathogens, 2022, 18 (7), 29 p. ⟨10.1371/journal.ppat.1010305⟩
Journal articles hal-03738417v1

Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation

Antoine Guillon , Jeoffrey Pardessus , Guillaume L'Hostis , Cindy Fevre , Céline Barc et al.
Journées d'Animation Scientifique de la FéRI 2022- FéRI Scientific Days 2022, Région Centre Val de Loire, Jul 2022, Tours, France
Conference poster hal-03735811v1

Mucosal administration of anti-bacterial antibody (Ab) provides long-term cross-protection against Pseudomonas aeruginosa respiratory infection

Aubin Pitiot , Marion Ferreira , Christelle Parent , Chloé Boisseau , Mélanie Cortes et al.
Journées d'Animation Scientifique de la FéRI 2022 - FéRi Scientific Days 2022, Fédération de Recherche en Infectiologie (FéRI), Centre Val de Loire, Jul 2022, Joué-Lès-Tours, France
Conference papers hal-03735460v1
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Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein

Antoine Guillon , Deborah Bréa-Diakite , Adeline Cezard , Alan Wacquiez , Thomas Baranek et al.
EMBO Journal, 2022, 41 (12), pp.e108306. ⟨10.15252/embj.2021108306⟩
Journal articles hal-03687124v2

In silico and in vitro mapping of specificity patterns of glycosaminoglycans towards cysteine cathepsins B, L, K, S and V

K.K. Bojarski , J. Sage , Gilles Lalmanach , F. Lecaille , S.A. Samsonov et al.
Journal of Molecular Graphics and Modelling, 2022, 113, pp.108153. ⟨10.1016/j.jmgm.2022.108153⟩
Journal articles hal-03677293v1
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Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018)

Stéphane Bretagne , Karine Sitbon , Marie Desnos-Ollivier , Dea Garcia-Hermoso , Valérie Letscher-Bru et al.
mBio, 2022, pp.e0092022. ⟨10.1128/mbio.00920-22⟩
Journal articles hal-03658122v1
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Overview about Candida auris: what's up 12 years after its first description?

Guillaume Desoubeaux , Alix T Coste , Christine Imbert , Christophe Hennequin
Journal of Medical Mycology = Journal de Mycologie Médicale, 2022, 32 (2), pp.101248. ⟨10.1016/j.mycmed.2022.101248⟩
Journal articles hal-03554923v1
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Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases

Christophe Paget , Emilie Doz-Deblauwe , Nathalie Winter , Benoit Briard
Cells, 2022, 11 (7), 21 p. ⟨10.3390/cells11071188⟩
Journal articles hal-03690398v1

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions

Sonia Brun , Eloïne Bestion , Eric Raymond , Firas Bassissi , Zuzana Macek Jilkova et al.
Autophagy, 2022, 18 (3), pp.678-694. ⟨10.1080/15548627.2021.1988357⟩
Journal articles hal-03677289v1

Modulation of the expression and activity of cathepsin S in reconstructed human skin by neohesperidin dihydrochalcone

J. Sage , J. Renault , R. Domain , K.K. Bojarski , T. Chazeirat et al.
Matrix Biology, 2022, 107, pp.97-112. ⟨10.1016/j.matbio.2022.02.003⟩
Journal articles hal-03677291v1

Cathepsin V: Molecular characteristics and significance in health and disease

Fabien Lecaille , Thibault Chazeirat , Ahlame Saidi , Gilles Lalmanach
Molecular Aspects of Medicine, 2022, pp.101086. ⟨10.1016/j.mam.2022.101086⟩
Journal articles hal-03677295v1
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Lisa Reidy , Guillaume Desoubeaux , Julia Cardenas , Joshua Seither , Kristin Kahl et al.
Journal of Zoo and Wildlife Medicine, 2022, 53 (1), ⟨10.1638/2021-0070⟩
Journal articles hal-03687392v1

Synthesis, antibacterial and cytotoxic evaluation of cytosporone E and analogs

Walaa Ibraheem , Capucine Chaar , Emilie Camiade , Virginie Hervé , Delphine Fouquenet et al.
Journal of Molecular Structure, 2022, 1252, 12 p. ⟨10.1016/j.molstruc.2021.132135⟩
Journal articles hal-03509478v1
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TLR5 signalling is hyper-responsive in porcine cystic fibrosis airways epithelium

Isabelle Fleurot , Raquel López-Gálvez , Pascal Barbry , Antoine Guillon , Mustapha Si-Tahar et al.
Journal of Cystic Fibrosis, 2022, 21 (2), pp.e117-e121. ⟨10.1016/j.jcf.2021.08.002⟩
Journal articles hal-03556846v1
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Pneumocystis pneumonia: pitfalls and hindrances to establish a reliable animal model

Adélaïde Chesnay , Christophe Paget , Nathalie Heuzé-Vourc’h , Thomas Baranek , Guillaume Desoubeaux et al.
Journal of Fungi, 2022, 8 (2), pp.129. ⟨10.3390/jof8020129⟩
Journal articles hal-03687287v1
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Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study

Jean-Pierre Gangneux , Eric Dannaoui , Arnaud Fekkar , Charles-Edouard Luyt , Françoise Botterel et al.
The Lancet Respiratory Medicine, 2022, 10 (2), pp.180-190. ⟨10.1016/s2213-2600(21)00442-2⟩
Journal articles inserm-03587204v1
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Atteinte pulmonaire du déficit en alpha-1 antitrypsine. Recommandations pratiques pour le diagnostic et la prise en charge

J.-F. Mornex , M. Balduyck , M. Bouchecareilh , A. Cuvelier , R. Epaud et al.
Revue des Maladies Respiratoires, 2022, 39 (7), pp.633-656. ⟨10.1016/j.rmr.2022.06.002⟩
Journal articles hal-03844182v1
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Assessment of the safety and the anti-α-Gal immune response to an oral vaccine in captive-bred Humboldt penguins (Spheniscus humboldti)

Milan Thorel , Lourdes Mateos-Hernandez , Baptiste Mulot , Mouna Naila Azzouni , Adnan Hodžić et al.
Frontiers in Immunology, 2022, 13, pp.897223. ⟨10.3389/fimmu.2022.897223⟩
Journal articles hal-03687361v1
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The Novodiag® Stool parasites assay, an innovative high-plex technique for fast detection of protozoa, helminths and microsporidia in stool samples: a retrospective and prospective study

Sophie Hartuis , Rose-Anne Lavergne , Céline Nourrisson , Jaco Verweij , Guillaume Desoubeaux et al.
Parasite, 2022, 29, pp.1-8. ⟨10.1051/parasite/2022026⟩
Journal articles hal-03668002v1
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Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects

Thomas Sécher , Elsa Bodier-Montagutelli , Christelle Parent , Laura Bouvart , Mélanie Cortes et al.
Pharmaceutics, 2022, 14 (3), pp.671. ⟨10.3390/pharmaceutics14030671⟩
Journal articles hal-03687448v1

pAspergillosis in a colony of Humboldt penguins ( Spheniscus humboldti ) under managed care: a clinical and environmental investigation in a French zoological park

Estelle Cateau , Antoine Leclerc , Noémie Cartier , Isabel Valsechi , Éric Bailly et al.
Medical Mycology, 2022, 60 (7), pp.myac046. ⟨10.1093/mmy/myac046⟩
Journal articles hal-03699858v1
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Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection

Olivier Reynard , Claudia Gonzalez , Claire Dumont , Mathieu Iampietro , Marion Ferren et al.
Nature Communications, 2022, 13 (1), pp.6439. ⟨10.1038/s41467-022-33832-6⟩
Journal articles hal-03886267v1
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NLRP6 negatively regulates type 2 immune responses in mice

Pauline Chenuet , Quentin Marquant , Louis Fauconnier , Ali Youness , Manon Mellier et al.
Allergy, In press, ⟨10.1111/all.15388⟩
Journal articles hal-03770030v1
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Alternative Routes of Administration for Therapeutic Antibodies -State of the Art

Aubin Pitiot , Nathalie Heuzé-Vourc’h , Thomas Sécher
Antibodies, 2022, 11 (3), pp.56. ⟨10.3390/antib11030056⟩
Journal articles hal-03769100v1
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Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges

Olivier Terrier , Mustapha Si-Tahar , Mariette Ducatez , Christophe Chevalier , Andrés Pizzorno et al.
PLoS Pathogens, 2021, 17 (12), pp.e1010106. ⟨10.1371/journal.ppat.1010106⟩
Journal articles hal-03518306v1