Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis. - Plateforme Cytométrie Accéder directement au contenu
Article Dans Une Revue Molecular Vision Année : 2020

Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis.

Liem Trinh
  • Fonction : Auteur
Françoise Brignole-Baudouin
Aude Pauly
  • Fonction : Auteur
  • PersonId : 910700
Hong Liang

Résumé

To determine whether the ocular surface inflammation in uveitis mimics or counteracts intraocular inflammatory pathways by directly comparing T-helper (Th) lymphocytes Th1 and Th2 markers in conjunctival and ciliary body expression in endotoxin-induced uveitis (EIU). This study used the following inflammatory markers: chemokine receptor, CC chemokine receptor 4 (CCR4), and its ligand, macrophage-derived chemokine (MDC), to evaluate Th2 participation; chemokine receptor, CCR5, to evaluate the Th1 system; and its ligand, regulated on activation normal T cell expressed and secreted (RANTES), to evaluate both Th1 and Th2 systems.
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Dates et versions

hal-02619541 , version 1 (25-05-2020)

Identifiants

  • HAL Id : hal-02619541 , version 1
  • PUBMED : 19104678

Citer

Liem Trinh, Françoise Brignole-Baudouin, Aude Pauly, Hong Liang, Marianne Houssier, et al.. Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis.. Molecular Vision, 2020, 14, pp.2428-34. ⟨hal-02619541⟩
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