Search - Archive ouverte HAL Access content directly

Filter your results

201 Results
Deposit type : Fulltext
Image document

Statistical methods for deciphering intra-tumor hereterogeneity : challenges and opportunities for cancer clinical management

Judith Abecassis
Bioinformatics [q-bio.QM]. Université Paris sciences et lettres, 2020. English. ⟨NNT : 2020UPSLM065⟩
Theses tel-03228677v1
Image document

Determining the optimal number of independent components for reproducible transcriptomic data analysis

Ulykbek Kairov , Laura Cantini , Alessandro Greco , Askhat Molkenov , Urszula Czerwinska et al.
BMC Genomics, 2017, 18 (1), pp.712. ⟨10.1186/s12864-017-4112-9⟩
Journal articles inserm-02064099v1
Image document

Large scale evaluation of differences between network-based and pairwise sequence-alignment-based methods of dendrogram reconstruction

Daniel Gamermann , Arnau Montagud , J Alberto Conejero , Pedro Fernández de Córdoba , Javier F Urchueguía et al.
PLoS ONE, 2019, 14 (9), pp.e0221631. ⟨10.1371/journal.pone.0221631⟩
Journal articles inserm-02317883v1
Image document

Validation de biomarqueurs prédictifs de la réponse au traitement : extension des courbes de prédictivités à un critère de jugement censuré

Bassirou Mboup
Statistiques [math.ST]. Université Paris-Saclay, 2020. Français. ⟨NNT : 2020UPASR011⟩
Theses tel-03176621v1
Image document

Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer

Suzy M Scholl , Jonas Beal , Leanne de Koning , Elodie Girard , Marina Popovic et al.
EBioMedicine, 2020, 61, pp.103049. ⟨10.1016/j.ebiom.2020.103049⟩
Journal articles hal-03492821v1
Image document

Demarcation of Topologically Associating Domains Is Uncoupled from Enriched CTCF Binding in Developing Zebrafish

Yuvia A Perèz Rico , Emmanuel Barillot , Alena Shkumatava
iScience, 2020, 23 (5), pp.101046. ⟨10.1016/j.isci⟩
Journal articles hal-02872297v1
Image document

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

Valentina Boeva , Caroline Louis-Brennetot , Agathe Peltier , Simon Durand , Cecile Pierre-Eugene et al.
Nature Genetics, 2017, 49 (9), pp.1408-1413. ⟨10.1038/ng.3921⟩
Journal articles hal-01741718v1
Image document

Rôle de la phosphatase PRL-3 et de CRMP2 dans la migration et l'invasion du mélanome uvéal

Laura Duciel
Cancer. Université Paris Saclay (COmUE), 2018. Français. ⟨NNT : 2018SACLS233⟩
Theses tel-02304146v1
Image document

An autocrine ActivinB mechanism drives TGF β/Activin signaling in Group 3 medulloblastoma

Morgane Morabito , Magalie Larcher , Florence M G Cavalli , Chloé Foray , Antoine Forget et al.
EMBO Molecular Medicine, 2019, 6, pp.e9830. ⟨10.15252/emmm.201809830⟩
Journal articles hal-02347105v1
Image document

CinéBreast-factors influencing the time to first metastatic recurrence in breast cancer: Analysis of real-life data from the French ESME MBC database

P. Gougis , M. Carton , C. Tchokothe , M. Campone , F. Dalenc et al.
The Breast, 2020, 49, pp.17-24. ⟨10.1016/j.breast.2019.10.004⟩
Journal articles hal-02888468v1
Image document

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Florence Coussy , Rania El-Botty , Sophie Château-Joubert , Ahmed Dahmani , Elodie Montaudon et al.
Science Translational Medicine, 2020, 12 (531), pp.eaax2625. ⟨10.1126/scitranslmed.aax2625⟩
Journal articles hal-02508765v1
Image document

Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer

Sophie Vacher , Voreak Suybeng , Élodie Girard , Julien Masliah Planchon , Grégory Thomson et al.
Cancers, 2020, 12 (10), pp.2882. ⟨10.3390/cancers12102882⟩
Journal articles hal-03011747v1
Image document

A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport

Adham Safieddine , Emeline Coleno , Soha Salloum , Arthur Imbert , Abdel-Meneem Traboulsi et al.
Nature Communications, 2021, 12 (1), pp.1352. ⟨10.1038/s41467-021-21585-7⟩
Journal articles hal-03014936v2
Image document

Scaling ResNets in the Large-depth Regime

Pierre Marion , Adeline Fermanian , Gérard Biau , Jean-Philippe Vert
Preprints, Working Papers, ... hal-03697725v1
Image document


Joseph Boyd , Zelia Gouveia , Franck Perez , Thomas Walter
2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), Apr 2020, Iowa City, United States. pp.886-890, ⟨10.1109/ISBI45749.2020.9098696⟩
Conference papers hal-02976141v1
Image document

Bioimage Informatics for Phenomics

Thomas Walter
Bioinformatics [q-bio.QM]. Sorbonne Université, 2020
Habilitation à diriger des recherches tel-02981391v1
Image document

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma

W. Cacheux , V. Dangles-Marie , E. Rouleau , J. Lazartigues , E. Girard et al.
Oncotarget, 2018, 9 (1), pp.464-476. ⟨10.18632/oncotarget.23066⟩
Journal articles hal-01717339v1
Image document

Evaluation of least significant changes of pulse contour analysis-derived parameters

Hugues de Courson , Loic Ferrer , Grégoire Cane , Eric Verchère , Musa Sesay et al.
Annals of Intensive Care, 2019, 9 (1), pp.116. ⟨10.1186/s13613-019-0590-z⟩
Journal articles inserm-02467629v1
Image document

The CoLoMoTo Interactive Notebook: Accessible and Reproducible Computational Analyses for Qualitative Biological Networks

Aurélien Naldi , Céline Hernandez , Nicolas Levy , Gautier Stoll , Pedro Monteiro et al.
Frontiers in Physiology, 2018, 9, pp.n°680:1-13. ⟨10.3389/fphys.2018.00680⟩
Journal articles hal-01794294v2
Image document

kernelPSI: a Post-Selection Inference Framework for Nonlinear Variable Selection

Lotfi Slim , Clement Chatelain , Chloé-Agathe Azencott , Jean-Philippe Vert
36th International Conference on Machine Learning (ICML 2019), Jun 2019, Long Beach, CA, United States
Conference papers hal-02441304v1
Image document

CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data

Judith Abécassis , Fabien Reyal , Jean-Philippe Vert
Nature Communications, 2021, 12 (1), pp.5352. ⟨10.1038/s41467-021-24992-y⟩
Journal articles hal-03510272v1
Image document

Graph-Based Spatial Segmentation of Health-Related Areal Data

Vivien Goepp , Jan van de Kassteele
Computational Statistics and Data Analysis, 2022, ⟨10.48550/arXiv.2206.06752⟩
Journal articles hal-03474990v1
Image document

Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

Maroulio Pertesi , Maxime Vallée , Xiaomu Wei , Maria Revuelta , Perrine Galia et al.
Leukemia, 2019, 33 (9), pp.2324-2330. ⟨10.1038/s41375-019-0452-6⟩
Journal articles hal-02190723v1
Image document

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

Nasim Mavaddat , Antonis C. Antoniou , Thea Mooij , Maartje Hooning , Bernadette Heemskerk-Gerritsen et al.
Breast Cancer Research, 2020, 22 (1), pp.8. ⟨10.1186/s13058-020-1247-4⟩
Journal articles inserm-02445596v1
Image document

A new hybrid record linkage process to make epidemiological databases interoperable: application to the GEMO and GENEPSO studies involving BRCA1 and BRCA2 mutation carriers

Yue Jiao , Fabienne Lesueur , Chloé-Agathe Azencott , Maïté Laurent , Noura Mebirouk et al.
BMC Medical Research Methodology, 2021, 21 (1), pp.155. ⟨10.1186/s12874-021-01299-6⟩
Journal articles inserm-03313811v1
Image document

National recommendations of the French Genetics and Cancer Group - Unicancer on the modalities of multi-genes panel analyses in hereditary predispositions to tumors of the digestive tract

Marion Dhooge , Stéphanie Baert-Desurmont , Carole Corsini , Olivier Caron , Nadine Andrieu et al.
European Journal of Medical Genetics, 2020, 63 (12), pp.104080. ⟨10.1016/j.ejmg.2020.104080⟩
Journal articles inserm-03182974v1
Image document

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel Barnes , Matti Rookus , Lesley Mcguffog , Goska Leslie , Thea Mooij et al.
Genetics in Medicine, 2020, 22 (10), pp.1653-1666. ⟨10.1038/s41436-020-0862-x⟩
Journal articles inserm-03193473v1
Image document

Qualitative dynamics semantics for SBGN process description

Adrien Rougny , Christine Froidevaux , Laurence Calzone , Loïc Paulevé
BMC Systems Biology, 2016, ⟨10.1186/s12918-016-0285-0⟩
Journal articles hal-01332679v1
Image document

RNF: a general framework to evaluate NGS read mappers

Karel Brinda , Valentina Boeva , Gregory Kucherov
Bioinformatics, 2016, 32 (1), pp.136-139. ⟨10.1093/bioinformatics/btv524⟩
Journal articles hal-01220199v2
Image document

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

Maud Borensztein , Laurène Syx , Katia Ancelin , Patricia Diabangouaya , Christel Picard et al.
Nature Structural and Molecular Biology, 2017, ⟨10.1038/nsmb.3365⟩
Journal articles hal-03021809v1